Take I-95 or the PA Turnpike to Route 476, "The Blue Route".  Take Route 476 (north from I-95, south from the Turnpike) to Exit 3, Springfield, Lima.  Follow the signs for Route 1 north.  Take Route 1 north 0.4 miles to Sproul Road, Route 320.  Turn left (north) onto Sproul Road (320).  Cardinal O'Hara is 0.6 miles down on the right.